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<p style="max-width: 100%; min-height: 1em; color: rgb(62, 62, 62); font-size: 16px; line-height: 25.6px; white-space: normal; box-sizing: border-box !important; word-wrap: break-word !important; background-color: rgb(255, 255, 255);"><img class="__bg_gif" data-ratio="0.10555555555555556" src="http://mmbiz.qpic.cn/mmbiz/M2H0aGBjWUTRia7nqkArYeKZUqEfdmpNibMPiaZk4gvlWk5v5lUKyXhjJP4CENKQeQt5HI8zwcTCWJOkicfWJiatdJQ/0?wx_fmt=gif" data-type="gif" data-w="720" style="line-height: 25.6px; box-sizing: border-box !important; word-wrap: break-word !important; width: auto !important; visibility: visible !important;" /></p><p><br /></p><section data-role="outer" label="Powered by gulangu" style="max-width: 100%; color: rgb(62, 62, 62); font-size: 16px; line-height: 25.6px; white-space: normal; font-family: 微软雅黑; box-sizing: border-box !important; word-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section class="" style="padding: 10px; max-width: 100%; box-sizing: border-box !important; word-wrap: break-word !important; background-image: url(http://mmbiz.qpic.cn/mmbiz_png/YbTq6LNicqJ4V3R4EZrgQeRSiabghY6Axl34bZEemgsuQvWZuJxrgMFk5OTou0Rl0sNOXJvCicHoI1cYAe861Qtvw/0?wx_fmt=png); background-size: auto; background-position: 50% 50%; background-repeat: repeat;"><span style="line-height: 1.6; font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif;">近日，中山大学附属第一医院副院长何晓顺团队成功实现两例“不中断血流”肝移植，破解了器官移植领域的一项世界性难题。</span><br /></section></section><p><br /></p><p>传统人体器官移植包括器官获取、保存及植入等“三部曲”，在这一过程中，器官一旦离开捐献者体内，便处于“无血流供应”状态，时间达数小时至数十小时不等，不可避免地遭受缺血、冷保存及再灌注的损伤，导致肝功能受损。这也是影响器官移植疗效乃至导致移植失败的最主要原因。 </p><p style="text-align:center"><img data-s="300,640" data-type="jpeg" src="http://mmbiz.qpic.cn/mmbiz_jpg/dx3KibwtDhvebPiaddrsuicZDORM9uQNIg5kSASMiakRSSf5bXDAvPBuaGWriczicUBKXiaItOFQLyaz7rQMKSo82WHOw/0?wx_fmt=jpeg" class="" data-ratio="0.6203703703703703" data-w="540" /></p><p>全球首例“无缺血”人体肝移植成功破解</p><p><br /></p><p>至于“无缺血”肝移植技术，何晓顺介绍说，摘取器官前，医生先将连接肝脏的血管接入“多器官功能修复系统”，在断掉原有血液供应的同时，由该系统替代人体的供血机制，从而实现平稳过渡。供肝植入移植受体时，将受体血管接入该系统，在由受体的血液循环系统接管的同时将机器撤离。在这个过程中，肝脏里的血一直是热的。</p><p><br /></p><p>为了提高器官移植的疗效，中山大学附属第一医院副院长、器官移植科学术带头人何晓顺团队从数年前开始致力于自主研发“多器官功能修复系统”。这种“多器官功能修复系统”可在手术前模拟人体的机制，为器官提供血液，从而提高器官功能。其过程是：摘取器官前，医生先将连接肝脏的血管接入“多器官功能修复系统”，在断掉原有血液供应的同时，由“多器官功能修复系统”替代人体的供血机制，从而实现平稳过渡。供肝植入移植受体时，将受体的血管接入“多器官功能修复系统”，在由受体的血液循环系统“接管”的同时，将机器撤离。在这个过程中，肝脏里的“血一直是热的”。5年来，何晓顺团队在大动物身上进行了近百例移植实验，并获得了一系列技术创新。</p><p><span style="line-height: 1.6;">全球首例“无缺血”人体肝移植成功破解</span></p><p style="text-align:center"><img data-s="300,640" data-type="jpeg" src="http://mmbiz.qpic.cn/mmbiz_jpg/dx3KibwtDhvebPiaddrsuicZDORM9uQNIg5JHbECic2sicJ77ArWVE1KzmndRsWSgWTcQbHmsHRBn4UXibAr0CXvL3bQ/0?wx_fmt=jpeg" class="" data-ratio="0.6203703703703703" data-w="540" /></p><p>中山大学附属第一医院何晓顺团队另辟蹊径，于7月23日在为一名肝硬化合并小肝癌的患者进行肝脏移植时，创造了“不中断血流”的新纪录，并于8月8日成功开展了第二例同类手术。这一创新成功破解了器官移植的世界性难题，有望改写世界器官移植事业的历史，推动我国成为器官移植这项医学尖端技术的领跑者。</p><p><br /></p><p>术后患者肝功能指标明显优于传统肝移植手术。何晓顺介绍，这项新技术未来还可延伸至心、肺、肾等的移植上。</p><p><br /></p><p>“这项技术是对现有器官移植技术颠覆性创新，更是我国学者对整个器官移植领域的重大贡献。”著名器官移植专家、中国工程院院士王学浩“点赞”这项新技术。他指出，该项技术将使器官功能得到最大的保护，器官的损伤将降至最低，甚至有可能降低排斥反应的发生，将能极大改善器官移植受体的疗效。</p><p><br /></p><p><br /></p><p style="max-width: 100%; min-height: 1em; color: rgb(62, 62, 62); font-size: 16px; line-height: 25.6px; white-space: normal; font-family: 微软雅黑; box-sizing: border-box !important; word-wrap: break-word !important; background-color: rgb(255, 255, 255);"><span style="max-width: 100%; font-size: 14px; text-indent: 0em; font-family: Arial, Verdana, sans-serif; line-height: 1.75em; box-sizing: border-box !important; word-wrap: break-word !important;">地址：广州市天河区银利街银利茶叶博览中心E栋4楼E4030室 </span></p><p style="max-width: 100%; min-height: 1em; color: rgb(62, 62, 62); text-indent: 0em; white-space: normal; font-size: 12px; font-family: Arial, Verdana, sans-serif; line-height: 1.75em; box-sizing: border-box !important; word-wrap: break-word !important; background-color: rgb(255, 255, 255);"><span style="max-width: 100%; font-size: 14px; line-height: 1.75em; box-sizing: border-box !important; word-wrap: break-word !important;">邮编：510507</span></p><p style="max-width: 100%; min-height: 1em; color: rgb(62, 62, 62); text-indent: 0em; 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发表于 2020-10-19 23:13:22