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<section data-role="paragraph" data-color="rgb(182, 228, 253)" data-custom="rgb(182, 228, 253)"><section><section><section><section powered-by="gulangu"><section><section><section><section powered-by="gulangu"><section><section><section><section powered-by="gulangu"><section><section><section><section powered-by="gulangu"><section><section><section><section><p><p><img src="image/20201014/86b79d371e9862b01189f0252a03b2cd_1.png" /></p></p></section><section><section><span><strong></strong></span></section><p><span>医疗器械媒体报道先锋</span></p><p><span>分享专业医疗器械知识</span></p></section><section><section><section><span>关注</span></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section></section><section><section><section><section><section><section><br /></section><section powered-by="gulangu"><p><span>中国科研团队近日在《科学》杂志上公开表示发现了两种可有效阻断新冠病毒感染的人源单克隆抗体，有望用于抗新冠药物和疫苗的研发。</span></p><p><br /></p><p><span>目前两个抗体已在相关公司进行产品转化，未来有望用于新冠患者临床治疗。</span></p><p><br /></p></section><section powered-by="gulangu"><section data-tools="新媒体排版" data-id="1223097" data-style-type="undefined"><section data-mpa-template-id="258091" data-mpa-color="#ffffff"><section data-role="outer" label="Powered by gulangu"><section data-css="border-color: initial;border-style: none;border-width: 0px;margin-top: 5px;text-align: center"><section data-css="border-bottom: 3px solid rgb(82, 167, 250);border-left-color: rgb(82, 167, 250);border-right-color: rgb(82, 167, 250);border-top-color: rgb(58, 188, 255);display: inline-block;font-size: 1em;padding: 0.5em"><p><span><strong>中国团队发现可阻断新冠病毒感染的人源单克隆抗体</strong></span></p></section></section></section></section></section><p><br /></p><p><span>中国科研团队近日在美国《科学》杂志在线发表论文说，<strong>他们发现了两种可有效阻断新冠病毒感染的人源单克隆抗体，有望用于抗新冠药物和疫苗的研发。</strong></span></p><p><br /></p><p><span>中国首都医科大学、中国科学院微生物研究所、中国科学院天津工业生物技术研究所、深圳市第三人民医院等多家单位参与这项研究。<strong>研究人员从一名新冠康复患者的外周血单核细胞中分离出4种人源单克隆抗体。</strong></span></p><p><span><br /></span></p><p><br /></p><p><span>实验显示，这4种抗体对新型冠状病毒均有中和能力。其中，分别被称为B38和H4的两种抗体能够阻断新冠病毒刺突蛋白的受体结合域与其受体“血管紧张素转化酶2（ACE2）”的结合</span></p></section><section powered-by="gulangu"><br /></section><section powered-by="gulangu"><p><span>此前多项揭示新冠病毒感染机制的研究表明，该病毒主要通过其表面刺突蛋白受体结合域与人体细胞上的ACE2结合实现感染。</span></p><p><br /></p><p><span>实验显示，B38和H4分别识别受体结合域的不同表位，小鼠实验证实了这两种抗体能降低感染小鼠肺部的病毒量，展现出了治疗效果。两种抗体还可被混合使用以便更有效抑制病毒感染。</span></p><p><br /></p><p><span>研究团队进一步解析了新冠病毒刺突蛋白受体结合区域与B38形成的复合物结构，从而揭示了B38阻断病毒感染的分子机制。</span></p></section><section powered-by="gulangu"><p><br /></p><p><span>研究人员介绍，最新研究表明，<strong>筛选到的两种抗体具有进一步被开发成治疗新冠病毒感染药物的潜力，并为疫苗设计提供了基础</strong>。目前两个抗体已在相关公司进行产品转化，未来有望用于新冠患者临床治疗。</span></p></section><section powered-by="gulangu"><p><br /></p></section><section powered-by="gulangu"><section data-tools="新媒体排版" data-id="1223097" data-style-type="undefined"><section data-mpa-template-id="258091" data-mpa-color="#ffffff"><section data-role="outer" label="Powered by gulangu"><section data-css="border-color: initial;border-style: none;border-width: 0px;margin-top: 5px;text-align: center"><section data-css="border-bottom: 3px solid rgb(82, 167, 250);border-left-color: rgb(82, 167, 250);border-right-color: rgb(82, 167, 250);border-top-color: rgb(58, 188, 255);display: inline-block;font-size: 1em;padding: 0.5em"><p><span><strong>什么时候能用上新冠疫苗？</strong></span></p></section></section></section></section></section><p><br /></p><p><span>近日，<strong>中央疫情防控指导组专家组成员、中国工程院院士、天津中医药大学校长张伯礼</strong>登上央视“开讲啦”。</span><br /></p><p><br /></p><p><p><img src="image/20201014/c0ebebae36cb04f31345ff7008fb0ab9_2.png" /></p><br /></p></section><section powered-by="gulangu"><p><br /></p><p><span>对于疫苗问题，张伯礼院士解答：“中国疫苗的研制走在世界前列，国内目前已经有三支疫苗批准上临床了。走在最前面的是陈薇院士所做的RNA的疫苗，一期一百零八例，已经评价完成。现在二期五百例，已经入组全部完毕。如果这期顺利的话，她就要开展第三期的实验。”<br /></span></p><p><br /></p><p><span>但是他表示，下一步的关键就是产能，疫苗成功了，我们是十四亿人口了，产能一般的疫苗大概只能供也就一千万人。一千万人太少了，所以我们会扩大产能。扩大产能也是有限的，也是有一个时间的。</span></p></section><section powered-by="gulangu"><p><br /></p></section><section powered-by="gulangu"><section data-tools="新媒体排版" data-id="1223097" data-style-type="undefined"><section data-mpa-template-id="258091" data-mpa-color="#ffffff"><section data-role="outer" label="Powered by gulangu"><section data-css="border-color: initial;border-style: none;border-width: 0px;margin-top: 5px;text-align: center"><section data-css="border-bottom: 3px solid rgb(82, 167, 250);border-left-color: rgb(82, 167, 250);border-right-color: rgb(82, 167, 250);border-top-color: rgb(58, 188, 255);display: inline-block;font-size: 1em;padding: 0.5em"><p><span><strong>口罩还要戴一年？</strong></span></p></section></section></section></section></section><p><br /></p></section><section powered-by="gulangu"><p><span>此外，#张伯礼称一年内口罩还是摘不掉#上了微博热搜。<br /></span></p><p><br /></p></section><section powered-by="gulangu"><section><p><img src="image/20201014/6a9706c781316f979fff3aa45d9b73fd_3.png" /></p></section></section><section powered-by="gulangu"><p><br /></p><p><span>网友提问：夏天来了，我们什么时候才能摘掉口罩呢？张伯礼院士表示，即使疫情控制了，还是要戴口罩的。</span></p><p><br /></p><p><iframe src="https://v.qq.com/iframe/player.html?width=500&height=375&auto=0&vid=v09674xywiu&auto=0" width="100%" height="580" frameborder="0"></iframe></p><p><br /></p></section><section powered-by="gulangu"><p><span>张伯礼说：“新冠从现在看，它和温度没有那么明确的关系。所以像印度尼西亚、印度温度都挺高，但是现在它传染的也很多。即使疫情控制了，我想还是要戴口罩的，还真是养成这种习惯。我估计这个口罩，在一年之内，起码到明年这时候是摘不掉的，一定要做好这种准备。”</span></p><p><br /></p></section><section powered-by="gulangu"><section data-tools="新媒体排版" data-id="1223097" data-style-type="undefined"><section data-mpa-template-id="258091" data-mpa-color="#ffffff"><section data-role="outer" label="Powered by gulangu"><section data-css="border-color: initial;border-style: none;border-width: 0px;margin-top: 5px;text-align: center"><section data-css="border-bottom: 3px solid rgb(82, 167, 250);border-left-color: rgb(82, 167, 250);border-right-color: rgb(82, 167, 250);border-top-color: rgb(58, 188, 255);display: inline-block;font-size: 1em;padding: 0.5em"><p><strong><span>中国疾控中心：</span></strong></p><p><strong><span>三种情况下仍建议戴口罩</span></strong></p></section></section></section></section></section><p><br /></p><p><iframe src="https://v.qq.com/iframe/player.html?width=500&height=375&auto=0&vid=u09682aq3yh&auto=0" width="100%" height="580" frameborder="0"></iframe></p><p><br /></p></section><section powered-by="gulangu"><section><section><span>关于戴口罩的问题，中国疾控中心也给出最新建议。在5月17日下午国务院联防联控机制召开的新闻发布会上，中国疾控中心研究员冯录召建议在以下三种情况下建议佩戴口罩。</span></section><section><span><br /></span></section></section></section><section powered-by="gulangu"><p><br /></p><p><span>一是在较封闭的公共场所，如公共交通工具、电梯、人多的公共场所内应配戴口罩；因为可能会接触一些感染状况不明的人员。</span></p><p><br /></p><p><span>二是生病时，尤其出现发热、咳嗽呼吸道症状时要戴口罩，避免传染给其他人；这不仅在疫情期间，将来在任何时候都要遵照这个原则，生病的人要戴口罩。</span></p><p><br /></p><p><span>三是在医院等特定环境内要戴口罩。比如去医院，不管是去医院就诊，还是陪同亲友去医疗机构，在医院这种场所内要佩戴口罩，所以这三种情况建议还是要规范佩戴口罩，来降低感染的风险。</span></p><p><br /></p></section><section powered-by="gulangu"><p><span>在低风险地区是不是还有必要全天佩戴口罩？</span></p><p><br /></p><p><span>冯录召回应：关于是否佩戴口罩，我们可以遵照一个原则，就是在通风条件良好并且能够保持比较好的、安全的社交距离的情况下，可以不佩戴口罩，具体包括以下情况：</span></p><p><br /></p><p><strong><span>一是在户外，比如公园、人比较少的街道，包括操场，是不需要佩戴口罩的。尤其在剧烈运动的时候更不能佩戴口罩。</span></strong></p><p><br /></p><p><strong><span>二是近期没有新发病例报告的低风险地区，其实我们在办公室、会议室、工地、学校，能够保持通风条件和相对的安全的社交距离的情况下，也不需要戴口罩。</span></strong><span></span></p><p><br /></p></section><section powered-by="gulangu"><p><span>来源：新华社、人民日报、中国青年报、央视新闻</span></p></section><section><br /></section></section></section></section></section></section><section data-role="outer" label="Powered by gulangu"><section data-role="paragraph" data-color="#757576"><section data-role="paragraph"><section><section><section data-brushtype="text"><strong>相关阅读</strong></section></section></section><section><section><br 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发表于 2020-10-14 12:20:13